Publications

Our key publications:

Laser Cell Manipulation:

• Binan L, et al. (2016) Live single-cell laser tag. Nat Commun. 2016 May 20;7:11636. pdf

• Binan L, et al. (2019) Opto-magnetic capture of individual cells based on visual phenotype. eLife 2019;8:e45239. PDF

• Bélisle JM, et al. (2008) Patterning protein concentration using laser-assisted adsorption by photobleaching, LAPAP. Lab Chip. 2008 Dec;8(12):2164-7. PDF

OCT & Biomechanics of the Eye:

• Sayah DN, Mazzaferri J, Descovich D, Costantino S, Lesk MR. (2020) The Association Between Ocular Rigidity and Neuroretinal Damage in Glaucoma. Investigative Ophtalmology & Visual Science November 2020, Vol.61, 11. pdf

• Mazzaferri J, et al.(2017) Open-source algorithm for automatic choroid segmentation of OCT volume reconstructions. Sci Rep. 2017 Feb 9;7. pdf

• L. Beaton, et al. (2015). Non-invasive measurement of choroidal volume change and ocular rigidity through automated segmentation of high-speed OCT imaging. Biomedical Optics Express. 6(5): 1694-1706. pdf

Publications - per year

2023:

• Massis Solano M, Belanger Nzakimuena C, Dumas R, Lesk M, Costantino S (2023) Ocular rigidity and choroidal thickness changes in response to microgravity: A case study. American Journal of Ophthalmology Case Reports, Volume 32,2023,101940,ISSN 2451-9936 pdf

• This S, Costantino S, Melichar HJ (2023) Predicting T cell activation based on intracellular calcium fluctuations. BioRxiv preprint

• Desjardins-Lecavalier N, Annis MG, Nowakowski A, Kiepas A, Binan L, Roy J, Modica M, Hebert S, Kleinman CL, Siegel PM, Costantino S (2023) Migration speed of captured breast cancer subpopulations correlates with metastatic fitness. J Cell Sci 2023 Jun 14;jcs.260835. PMID: 37313743 pdf

• Dumas R, Lacourse M, Kassem R, Lesk MR, Costantino S (2023) Quantification of Hypotony Maculopathy Using Spectral-Domain Optical Coherence Tomography. J Glaucoma 2023 Apr 1;32(4):287-292 doi: 10.1097/IJG.0000000000002161.PMID: 36729657 pdf

• Desjardins-Lecavalier N, Modica G, Costantino S. (2023) Laser-Assisted Single-Cell Labeling and Capture.Methods Mol Biol. 2023;2614:357-368. doi: 10.1007/978-1-0716-2914-7_21. PMID: 36587135 pdf

2022:

• Solano MM, Richer E, Cheriet F, Lesk MR, Costantino S. (2022) Mapping Pulsatile Optic Nerve Head Deformation Using OCT. Ophthalmol Sci. 2022 Aug 6;2(4):100205. doi: 10.1016/j.xops.2022.100205. eCollection 2022 Dec. PMID: 36531582 pdf

• Moldoveanu D, Ramsay L, Lajoie M, Anderson-Trocme L, Lingrand M, Berry D, Perus LJM, Wei Y, Moraes C, Alkallas R, Rajkumar S, Zuo D, Dankner M, Xu EH, Bertos NR, Najafabadi HS, Gravel S, Costantino S, Richer MJ, Lund AW, Del Rincon SV, Spatz A, Miller WH Jr, Jamal R, Lapointe R, Mes-Masson AM, Turcotte S, Petrecca K, Dumitra S, Meguerditchian AN, Richardson K, Tremblay F, Wang B, Chergui M, Guiot MC, Watters K, Stagg J, Quail DF, Mihalcioiu C, Meterissian S, Watson IR. (2022).Spatially mapping the immune landscape of melanoma using imaging mass cytometry. Sci Immunol. 2022 Apr;7(70):eabi5072. pdf

• Sayah DN, Mazzaferri J, Descovich D, Costantino S, Lesk MR. (2022). Ocular rigidity and neuroretinal damage in patients with vasospasticity: a pilot study. Can J Ophthalmol. 2022 Mar 28:S0008-4182(22)00052-7. pdf

• Roversi K, Tabatabaei M, Desjardins-Lecavalier N, Balood M, Crosson T, Costantino S, Griffith M, Talbot S, Boutopoulos C. Nanophotonics Enable Targeted Photothermal Silencing of Nociceptor Neurons. Small. 2022 Apr;18(14):e2103364.

2021:

• Sayah DN, Szigiato AA, Mazzaferri J, Descovich D, Duval R, Rezende FA, Costantino S, Lesk MR. Correlation of ocular rigidity with intraocular pressure spike after intravitreal injection of bevacizumab in exudative retinal disease. Br J Ophthalmol. 2021 Mar;105(3):392-396

2020:

• Sayah DN, Mazzaferri J, Descovich D, Costantino S, Lesk MR. The Association Between Ocular Rigidity and Neuroretinal Damage in Glaucoma. Invest Ophthalmol Vis Sci. 2020 Nov 2;61(13):11. pdf

• Sayah DN, Zhou TE, Omri S, Mazzaferri J, Quiniou C, Wirth M, Côté F, Dabouz R, Desjarlais M, Costantino S, Chemtob S. Novel Anti-Interleukin-1β Therapy Preserves Retinal Integrity: A Longitudinal Investigation Using OCT Imaging and Automated Retinal Segmentation in Small Rodents. Front Pharmacol. 2020 Mar 12;11:296. pdf

• Hsu BE, Roy J, Mouhanna J, Rayes RF, Ramsay L, Tabariès S, Annis MG, Watson IR, Spicer JD, Costantino S, Siegel PM. C3a elicits unique migratory responses in immature low-density neutrophils. Oncogene. 2020 Mar;39(12):2612-2623. pdf

2019:

• L. Binan, F. Bélanger, J-F. Lemay, J-C. Pelletier-De Koninck JC, J. Roy, E. Drobetsky, H. Wurtele, S. Costantino. Opto-magnetic capture of individual cells based on visual phenotype. eLife Apr 10;8 (2019). pdf

• P. Ghesquière, A.Elsherbiny, E. Fortier, M. McQuaid, J. Mazzaferri, F. Bélanger, F. Cheriet, E. Drobetsky, H. Wurtele, S. Costantino. An open-source implementation for fully automated quantification of DNA fibers. DNA Repair Feb;74:26-37(2019). pdf

• L. Binan, E. Drobetsky, S. Costantino. Exploiting Molecular Barcodes in High-Throughput Cellular Assays. SLAS Technol. 2019 Jun;24(3):298-307 pdf

2018:

• J. Mazzaferri, B. Larrivee, B. Cakir, P. Sapieha, S. Costantino. A machine learning approach for automated assessment of retinal vasculature in the oxygen induced retinopathy model Scientific Reports. Mar 2;8(1):3916 (2018). pdf

We are currently updating this website. For earlier years, find us on PubMed or our Archived Website.